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SCIENTIFIC DOMAIN PROGRAM: MOLECULAR BASES OF MEDICINE

Day 1: 20.10.2025

Educational Course in Research

1300–1530 Educational course in research “Antimicrobial resistance: from mechanisms to research-driven strategies to combat it”

  • Location: Teaching Block 1 “Leonid Cobîleanschi”, Department of Pharmacology and Clinical Pharmacology, Room 7, 4th floor, 27 Nicolae Testemițanu Street, Chișinău
  • MODERATORS

Lucia Țurcan, PhD in Medical Sciences, Associate Professor, Department of Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Diana Spătaru, PhD in Medical Sciences, University Assistant, Discipline of Epidemiology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

  • SECRETARIES

Ina Guțu, PhD in Medical Sciences, Associate Professor, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

PROGRAM

1300–1315 Participant registration

1315–1325 Welcome speech

Lucia Țurcan, PhD in Medical Sciences, Associate Professor, Department of Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1325–1350 Antimicrobial resistance – molecular mechanisms and current pharmacological challenges

Ina Guțu, PhD in Medical Sciences, Associate Professor, Department of Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1350–1355 Questions and discussions

1355–1420 Rational antibiotic use and pathways to combat antimicrobial resistance (AMR): from practice to policy – Antimicrobial Stewardship Program

Lucia Țurcan, PhD in Medical Sciences, Associate Professor, Department of Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1420–1425 Questions and discussions

1425–1450 Surveillance of antimicrobial resistance – national epidemiological data and intervention strategies

Diana Spătaru, PhD in Medical Sciences, University Assistant, Discipline of Epidemiology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1450–1455 Questions and discussions

1455–1520 Pharmacological perspectives in developing combined antimicrobial therapies

Nicolae Bacinschi, Dr. Habil. in Medical Sciences, University Professor, Head of the Department of Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1520–1530 Questions and discussions

CREATIVE IDEATION SESSION

1300–1830 Creative Ideation SessionFrom patient to genetic test result

  • Location: Center for Personalized Medicine, Genetics Laboratory, Teaching Block No. 1 “Leonid Cobîleanschi” (6th floor), Room 610, 27 Nicolae Testemițanu Street, Chișinău, MD-2025, Republic of Moldova
  • MODERATORS

Ghenadie Curocichin, Dr. Habil. in Medical Sciences, University Professor, Department of Family Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

  • SECRETARIES

Elena Chesov, PhD in Medical Sciences, University Assistant, Department of Molecular Biology and Human Genetics, “Nicolae Testemițanu” State University of Medicine and Pharmacy

PROGRAM

1300–1330 Participant registration

1330–1400 Welcome speech. From patient to result: key stages of genetic analysis in the laboratory

Ghenadie Curocichin, Dr. Habil. in Medical Sciences, University Professor, Department of Family Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1400–1430 Biological sample collection and registration of specimens

Cristina Butovscaia, scientific researcher, Personalized Medicine Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Anastasia Buza, Master in Molecular Biology, scientific researcher, Personalized Medicine Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1430–1600 DNA isolation from the collected sample

Elena Chesov, PhD in Medical Sciences, University Assistant, Department of Molecular Biology and Human Genetics; scientific researcher, Genetics Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Stela Racoviță, PhD in Medical Sciences, University Assistant, Department of Molecular Biology and Human Genetics; scientific researcher, Genetics Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1600–1630 Quality and quantity assessment of extracted DNA by spectrophotometric method

Stela Racoviță, PhD in Medical Sciences, University Assistant, Department of Molecular Biology and Human Genetics; scientific researcher, Genetics Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Elena Chesov, PhD in Medical Sciences, University Assistant, Department of Molecular Biology and Human Genetics; scientific researcher, Genetics Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1630–1645 Break

1645–1700 Preparation of plates for TaqMan genotyping using the dried DNA method

Mădălina Hîncu, trainee scientific researcher, Genetics Laboratory within the Center for Personalized Medicine; Master’s student in “Molecular Technologies in Health”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Maria Doni, trainee scientific researcher, Genetics Laboratory within the Center for Personalized Medicine; Master’s student in “Molecular Technologies in Health”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1700–1730 Preparation of Master Mix solution for TaqMan genotyping

Maria Doni, trainee scientific researcher, Genetics Laboratory within the Center for Personalized Medicine; Master’s student in “Molecular Technologies in Health”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Mădălina Hîncu, trainee scientific researcher, Genetics Laboratory within the Center for Personalized Medicine; Master’s student in “Molecular Technologies in Health”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1730–1800 Interpretation of TaqMan genotyping results

Anastasia Buza, Master in Molecular Biology, scientific researcher, Personalized Medicine Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Cristina Butovscaia, scientific researcher, Personalized Medicine Laboratory within the Center for Personalized Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1800–1830 Questions and discussions. Final conclusions and participant feedback

1300–1630 Creative Ideation SessionLegal framework and medications in sports

  • Location: Teaching Block No. 1 “Leonid Cobîleanschi”, 4th floor, Room 6, 27 Nicolae Testemițanu Street, Chișinău, MD-2025, Republic of Moldova
  • MODERATORS

Ina Pogonea, PhD in Medical Sciences, Associate Professor, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Tatiana Timercan, PhD in Medical Sciences, Associate Professor, Department of Biochemistry and Clinical Biochemistry, “Nicolae Testemițanu” State University of Medicine and Pharmacy; Chair of the Therapeutic Use Exemptions Committee

PROGRAM

1300–1330 Participant registration

1330–1345 Welcome speech

Ina Pogonea, PhD in Medical Sciences, Associate Professor, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1345–1400 Introduction and orientation to anti-doping in sport. Regulatory framework. Future trends

Artiom Jucov, PhD in Medical Sciences, Associate Professor, Department of Family Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1400–1415 Performance medication

Gheorghe Ștefanet, University Assistant, Department of Family Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Marcela Rusu, physician, Sports Medicine Center, Head of Department

1415–1430 Effects of medicines on athletic performance

Ina Pogonea, PhD in Medical Sciences, Associate Professor, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1430–1445 Nutritional alternatives vs. performance-enhancing medicines

Artiom Jucov, PhD in Medical Sciences, Associate Professor, Department of Family Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1445–1500 Safety of medication use in athletes

Tatiana Timercan, PhD in Medical Sciences, Associate Professor, Department of Family Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1500–1515 Practical skills. Doping control procedure

Ciofu Alina, clinical physician, Strășeni District Hospital; Principal Inspector, Service for Testing Prohibited Substances, ANAD

1515–1545 Debates. Q&A

1545–1600 Closing of the workshop

Workshops

1400–1600 Workshop in researchDrug interactions in complex therapy: a practical analysis through case studies

  • Location: Teaching Block No. 1 “Leonid Cobîleanschi”, 27 Nicolae Testemițanu Street, Department of Pharmacology and Clinical Pharmacology, 3rd floor, Room 7
  • MODERATORS

Lilia Podgurschi, PhD in Medical Sciences, Associate Professor, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

  • SECRETARIES

Anastasia Caracaș, University Assistant, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Mihalachi-Anghel Maria, University Assistant, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

PROGRAM

1400–1415 Participant registration

1415–1420 Welcome speech

1420–1500 Case study – evaluation of drug therapy in a patient with somatic diseases

Lilia Podgurschi, PhD in Medical Sciences, Associate Professor, Department of Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1500–1545 Case study – evaluation of antimicrobial therapy in the intensive care patient

Maria Mihalachi-Anghel, University Assistant, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Group activity: identifying interactions in the proposed prescription sheets

Anastasia Caracaș, University Assistant, Department of Pharmacology and Clinical Pharmacology, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1545–1600 Discussions, conclusions, and recommendations for good clinical practice

1500–1730 Workshop in researchThe health system’s response to sexual violence

  • Location: Department of Forensic Medicine, Study Room No. 2, Center of Forensic Medicine, 3rd floor, 8 Vl. Korolenco Street, Chișinău
  • MODERATORS

Andrei Pădure, Dr. Habil. in Medical Sciences, University Professor, Head of the Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Petru Glavan, University Assistant, Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

  • SECRETARIES

Natalia Toporeț, University Assistant, Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

PROGRAM

1500–1510 Participant registration

1510–1515 Welcome speech. Opening of the medical workshop

Andrei Pădure, Dr. Habil. in Medical Sciences, University Professor, Head of the Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1515–1545 Sexual violence. Consent to sexual intercourse

Petru Glavan, University Assistant, Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1545–1615 Case studies regarding consent to sexual intercourse

Petru Glavan, University Assistant, Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1615–1645 The health system’s response to cases of sexual violence

Natalia Toporeț, University Assistant, Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1615–1645 Rape kit. Simulation of the genito-anal examination and collection of biological samples

Natalia Toporeț, University Assistant, Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1645–1715 Questions and discussions. Closing of the medical workshop

Andrei Pădure, Dr. Habil. in Medical Sciences, University Professor, Head of the Department of Forensic Medicine, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1400–1630 Workshop in research “Modern technologies in the morpho-functional evaluation of spermatozoa”

  • Location: ANDROMED Plus Medical Center, 30A Drumul Schinoasei Street, Chișinău
  • MODERATORS

Ion Dumbraveanu, Dr. Habil. in Medical Sciences, Principal Scientific Researcher, Laboratory of Urology, Andrology and Reproductive Medicine

  • SECRETARIES

Iurii Arian, scientific researcher, Laboratory of Urology, Andrology and Reproductive Medicine

PROGRAM

1400–1410 Participant registration

1410–1415 Welcome speech

Ion Dumbraveanu, Dr. Habil. in Medical Sciences, Principal Scientific Researcher, Laboratory of Urology, Andrology and Reproductive Medicine

1415–1430 Visible and invisible changes in the spermogram

Iurii Arian, scientific researcher, Laboratory of Urology, Andrology and Reproductive Medicine

1430–1445 Techniques for performing the spermogram and determining sperm DNA fragmentation

Andrei Chiriac, scientific researcher, Laboratory of Urology, Andrology and Reproductive Medicine

Victoria Nofit, embryologist, “Andromed Plus” Fertility Center, Chișinău, Republic of Moldova

1445–1600 Performing and interpreting spermograms, determining oxidative stress and sperm DNA fragmentation

Anastasia Ambros, biologist, “Andromed Plus” Fertility Center, Chișinău, Republic of Moldova

1645–1715 Questions and discussions

1300–1700 On-line WorkshopExploring Classical Statistical Tests with RStudio – From Theory to Practice

  • Location: on-line
  • MODERATORS

Oleg Arnaut, Dr. Habil. in Medical Sciences, Associate Professor, Department of Physiology and Medical Biophysics, “Nicolae Testemițanu” State University of Medicine and Pharmacy

  • SECRETARIES

Oleg Arnaut, Dr. Habil. in Medical Sciences, Associate Professor, Department of Physiology and Medical Biophysics, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1300–1330 Participant registration. RStudio installation

1330–1500 Classical statistical tests I

Oleg Arnaut, Dr. Habil. in Medical Sciences, Associate Professor, Department of Physiology and Medical Biophysics, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1500–1530 Break

1530–1700 Classical statistical tests II

Oleg Arnaut, Dr. Habil. in Medical Sciences, Associate Professor, Department of Physiology and Medical Biophysics, “Nicolae Testemițanu” State University of Medicine and Pharmacy

LIVE RESEARCH LAB

1300–1900 Live Research LabThe Impact of Erroneous Immunohistochemical Procedure in Differential Morphopathological Diagnosis

  • Location: Teaching Block No. 1 “Leonid Cobîleanschi”, 27 Nicolae Testemițanu Street, Morphology Laboratory
  • MODERATORS

Valeriu David, PhD in Medical Sciences, Associate Professor, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

  • SECRETARIES

Valeria Pînzaru, trainee researcher, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

 

PROGRAM

1300–1330 Participant registration

1330–1345 Welcome speech

Valeriu David, PhD in Medical Sciences, Associate Professor, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1345–1645 Highlights in the technological chain methodology: sampling, orientation, processing, IHC procedure

Valeria Pînzaru, trainee researcher, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

IHC procedure: decoding (Bond/Max)

Mihaela Rotari, trainee researcher, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Optical microscopy vs. confocal microscopy

Tatiana Mărițoi, trainee researcher, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1645–1700 Break

1700–1730 Morphological evaluation by optical microscopy

David Valeriu, PhD in Medical Sciences, Associate Professor, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Morphological evaluation by confocal microscopy

Tatiana Mărițoi, trainee researcher, Morphology Laboratory, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1730–1800 Questions and discussions

1400–1730 Live Research Lab “In vivo techniques for evaluating hemodynamic effects in preclinical drug development”

  • Location: Molecular Medicine Center, Advanced Biomedical Technologies Laboratory, Teaching Building No. 1, 27 Testemițanu Street
  • MODERATORS

Ianoș Corețchi, PhD in Medical Sciences, Associate Professor, scientific researcher, Department of Pharmacology and Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Vladimir Topciu, University Assistant, trainee scientific researcher, Department of Pharmacology and Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

  • SECRETARIES

Ianoș Corețchi, PhD in Medical Sciences, Associate Professor, scientific researcher, Department of Pharmacology and Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

PROGRAM

1400–1430 Participant registration

1430–1500 Welcome speech

Ianoș Corețchi, PhD in Medical Sciences, Associate Professor, scientific researcher, Department of Pharmacology and Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1500–1550 Techniques for cannulating the femoral artery and vein in rats. Connection to PowerLab

Ianoș Corețchi, PhD in Medical Sciences, Associate Professor, scientific researcher, Department of Pharmacology and  Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Setting parameters for continuous recording of arterial blood pressure and heart rate

Vladimir Topciu, University Assistant, trainee scientific researcher, Department of Pharmacology and  Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1550–1600 Break

1600–1700 Administration of model drugs and real-time analysis of hemodynamic effects. Data processing and interpretation

Ianoș Corețchi, PhD in Medical Sciences, Associate Professor, scientific researcher, Department of Pharmacology and  Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

Vladimir Topciu, University Assistant, trainee scientific researcher, Department of Pharmacology and  Clinical Pharmacology; Advanced Biomedical Technologies Laboratory “Nicolae Testemițanu”, “Nicolae Testemițanu” State University of Medicine and Pharmacy

1700–1730 Questions and discussions